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Das Bild zeigt rechts ein Trichterglas mit blauer Flüssigkeit und Glasstab zum Umrühren. Daneben steht ein Reagenzglasständer mit Reagenzgläsern, die ebenfalls blaue Flüssigkeit enthalten. Im Hintergrund ist ein Forscher zu sehen, der in der rechten Hand eine Pipette hält.

Neurobiology of Dissociation

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Neurobiology of Dissociation

In the 5th edition of die DSM, a subtype of posttraumatic stress disorder (PTSD) was introduced which is characterized by additional symptoms of dissociation. Initial studies suggest that PTSD-patients of the dissociative subtype show increased symptom severity and benefit to a lesser extent from conventional trauma therapies compared to PTSD-patients without pronounced dissociative symptoms. The current proposal seeks to investigate the underlying neuronal mechanism of both PTSD subtypes: the well-known intrusive subtype as well as the recently introduced dissociative subtype. Both patient groups undergo a placebo-controlled, pharmacological challenge paradigm in the fMRI scanner. The continuation of the current project will not only ensure correlational analyses but enable to test a causal hypothesis of the etiology of dissociation and to determine dissociation-induced alterations in neural activations. The DFG funded study is performed in cooperation with Judith Daniels (Groningen).

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Assoc.-Prof. Dr. Judith Daniels