Effects of Antidepressant medication offset - AiDA

The main goal of the study is the identification of neurofunctional, behavioral and biological risk factors allowing to predict the relapse of a major depression episode after discontinuation of an antidepressant medication (ADM). Therefore a comprehensive range of diagnostical investigations (e.g. questionnaires, neuropsychological tests, fMRI, sMRI, EEG, blood and saliva analyses) is conducted with currently stably remitted patients, who formerly suffered from an unipolar major depressive disorder and are willing to discontinue their ADM independently. This is a bicentric project jointly funded by the DFG and the SFN, which is performed in Zurich (Translational Neuromodeling Unit, Department for Biomedical Engineering, ETH Zurich, PI: Quentin Huys) and Berlin (Research group Mind & Brain, Department of Psychiatry and Psychotherapy, Charité -Universtitätsmedizin Berlin, PI: Henrik Walter). For further information see here.